Cytoplasmic Modulators of Integrin Binding/Signalling
US5922570A · kind A · utility
2Cited by
1References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 5, 1996 |
| Grant date | Jul 13, 1999 |
| Priority date | — |
| Expiry date | Jan 5, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to purified and isolated polynucleotides encoding a polypeptide which specifically bind to a cytoplasmic portion of an integrin. Specifically, the invention provides a FLP-1-encoding polynucleotide and the polypeptide product of the gene. Expression vectors comprising the polynucleotide, antibodies which recognize the polypeptide, hybridomas which secrete the antibodies, and method to identify modulators of interaction of the polypeptide with .beta..sub.7 subunits sequences are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.