Patent · US Expired

Oxazolidinone antibacterial agent with tricyclic substituents

US5922707A · kind A · utility

3Cited by
7References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 2, 1997
Grant dateJul 13, 1999
Priority date
Expiry dateMay 2, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention provides novel oxazolidinone derivatives represented by chemical Formula (I), or pharmaceutically acceptable salts thereof: ##STR1## wherein X is NR.sub.1, CR.sub.2 R.sub.3, O, S, SO, or SO.sub.2 ; and Z is NR.sub.4, S, SO, SO.sub.2 or O. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci and streptococci, as well as anaerobic organisms such as bacteroides and clostridia species, and acid-fast organisms such as Mycobacterium tuberculosis and Mycobacterium avium.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.