Pyridine derivative
US5922743A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 7, 1997 |
| Grant date | Jul 13, 1999 |
| Priority date | — |
| Expiry date | Aug 7, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/56
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A pyridine derivative represented by the following formula: ##STR1## where R.sup.1 and R.sup.2 are as defined in the specification, or a salt thereof. These compounds directly or indirectly act on neuronal cells in vivo and are effective in the amelioration and curing of nerve disorders due to neuronal degeneration, such as, for example, traumatic symptoms and maladies, disorders induced by drugs such as alcohol and antineoplastic agents, inflammatory disorders, metabolic disorders observed in diabetes, and disorders due to idiopathic degeneration of peripheral nerves. These compounds are also effective for ameliorating and curing symptoms and maladies due to degeneration of central nerves, for example, Alzheimer's disease and cerebrovascular ischemia, Down's syndrome, Parkinson's disease, Huntington's chorea, diseases secondary to cerebral ischemia, cerebral infarction, intracerebral bleeding, head injuries, amnesia, and spinal neuropathy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.