Purifying Human Hemogloblin from transgenic pig red cells and plasmids containing pig globin nucleic acids
US5922854A · kind A · utility
16Cited by
2References
10Claims
0Family size
Inventors
Key dates
| Filing date | Aug 11, 1993 |
| Grant date | Jul 13, 1999 |
| Priority date | — |
| Expiry date | Aug 11, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the use of transgenic pigs for the production of human hemoglobin. The transgenic pigs of the invention may be used as an efficient and economical source of cell-free human hemoglobin that may be used for transfusions and other medical applications in humans. Also disclosed are the methods of purifying human hemoglobin from pig red cell lysate, and plasmids contained pig and human nucleic acid sequences for the production of transgenic pigs expressing human globin DNA sequences.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.