Amino acid derivatives, processes for preparing them and pharmaceutical compositions containing these compounds

US5922878A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Franz Esser · Ingelheim am Rhein, DE
• Gerd Schnorrenberg · Ingelheim am Rhein, DE
• Horst Dollinger · Schemmerhofen, DE
• Brigit Jung · Bingen, DE
• Erich Burger
• Georg Speck · Ingelheim am Rhein, DE

Key dates

• Filing date: May 27, 1997
• Grant date: Jul 13, 1999
• Expiry date: May 27, 2017

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to new amino acid derivatives of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein the group R.sup.2 is ##STR2## and R.sup.1, A, G, Y, Z and m have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin)-antagonists.