Adsorptive separation of 3-hydroxytetrahydrofuran enantiomers
US5928515A · kind A · utility
2Cited by
12References
11Claims
0Family size
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Key dates
| Filing date | Dec 12, 1997 |
| Grant date | Jul 27, 1999 |
| Priority date | — |
| Expiry date | Dec 12, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/02
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The chiral isomers of 3-hydroxytetrahyrofuran are separated by means of liquid chromatography using a stationary phase comprising a substituted polysaccharide carbamate. The separation may be performed using a simulated moving bed adsorbent system. Suitable mobile phase materials comprise a mixture of a light paraffin and a low molecular weight aliphatic alcohol such as a mixture of n-hexane and ethanol. Amylose is the preferred polysaccharide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.