Recombinant herpesvirus of turkeys and uses thereof
US5928648A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Feb 26, 1993 |
| Grant date | Jul 27, 1999 |
| Priority date | — |
| Expiry date | Feb 26, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/20022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a recombinant herpesvirus of turkeys comprises foreign DNA inserted into a site in the herpesvirus of turkeys genome which is not essential for replication of the herpesvirus of turkeys. The invention further relates to homology vectors which produce recombinant herpesvirus of turkeys by inserting foreign DNA into herpesvirus of turkeys genome. Genetically-engineered virus S-FPV-062 is described in the Materials and Methods section which follows. One advantage of recombinant HVT as live vaccines is that they may be engineered to express only a limited number of antigens that are needed to confer protective immunity to the corresponding pathogens. Consequently, host animals vaccinated with the recombinant HVT can be distinguished from those which have been infected with the wild type virus by the absence of antigens that are normally present in the wild type virus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.