Vectors for gene delivery
US5928913A · kind A · utility
41Cited by
2References
17Claims
0Family size
Inventors
Key dates
| Filing date | Mar 25, 1996 |
| Grant date | Jul 27, 1999 |
| Priority date | — |
| Expiry date | Mar 25, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/15022
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Herpesvirus amplicon preparations comprise an origin of replication, a packaging sequence, and at least one inserted gene under control of a promoter, suitable for use as an immunogen or vaccine, in association with helper herpesvirus or DNA, wherein the associated helper virus is of restricted replication competence in a normal host cell; for example where the associated helper virus has an inactivating defect in respect of a gene essential for production of infectious new virus particles, and where the amplicon carries an inserted gene necessary for the propagation of the helper virus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.