Human geranylgeranyl pyrophosphate synthetase
US5928924A · kind A · utility
12Cited by
6References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 11, 1998 |
| Grant date | Jul 27, 1999 |
| Priority date | — |
| Expiry date | Mar 11, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2799/026
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A human geranylgeranyl pyrophosphate synthetase polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for controlling morphology of cells. Antagonist against such polypeptides and their use as a therapeutic to treat cancer is also disclosed. Diagnostic assays are also disclosed which detect the presence of a mutated form of hGGPS and over-expression of the hGGPS protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.