Patent · US Expired

Serpin derived from human hypothalmus

US5929210A · kind A · utility

2Cited by
0References
2Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 23, 1997
Grant dateJul 27, 1999
Priority date
Expiry dateDec 23, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides nucleotide and amino acid sequences that identify and encode a novel serpin (CAPE) expressed in human hypothalamus. The present invention also provides for antisense molecules to the nucleotide sequences which encode CAPE, expression vectors for the production of purified CAPE, antibodies capable for binding specifically to CAPE, hybridization probes or oligonucleotides for the detection of CAPE-encoding nucleotide sequences, genetically engineered host cells for the expression of Cape, a pharmaceutical composition containing biologically active CAPE, a diagnostic test based on CAPE-encoding nucleic acid molecules, and treatment methods comprising administration of biologically active CAPE.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.