Patent · US Expired

Thermally responsive polymer monoliths

US5929214A · kind A · utility

77Cited by
0References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 25, 1998
Grant dateJul 27, 1999
Priority date
Expiry dateFeb 25, 2018

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01J2220/82
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

Porous polymer monoliths are made thermally responsive by functionalizing/grafting the pores with thermally responsive polymers and copolymers. Depending on the reaction conditions employed, the grafted polymer can either completely block flow through micrometer-sized pores in the monoliths or control the flow rate through the monoliths. The grafted monoliths are useful as thermal gates, thermal valves, and for isocratic hydrophobic interaction chromatography of proteins.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.