Reverse-turn mimetics and methods relating thereto
US5929237A · kind A · utility
51Cited by
2References
14Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 27, 1995 |
| Grant date | Jul 27, 1999 |
| Priority date | — |
| Expiry date | Oct 27, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Conformationally constrained compounds which mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetics have utility over a wide range of fields, including use as diagnostic and therapeutic agents. Libraries containing the reverse-turn mimetics of this invention are also disclosed, as well as methods for screening the same to identify biologically active members.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.