Controlled release preparations for cytotoxic or cytostatic drugs
US5932248A · kind A · utility
46Cited by
5References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 2, 1996 |
| Grant date | Aug 3, 1999 |
| Priority date | — |
| Expiry date | Dec 2, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A controlled release preparation comprises an ionic polymer matrix loaded with an active compound, particularly a pharmaceutically active compound such as doxorubicin or other cytotoxic or cytostatic drug, the active compound being complexed with a complexing agent such as a metal ion to modify the release of the active compound from the polymer matrix. The ionic polymer matrix may be provided in the form of microspheres, such as microspheres of crosslinked albumin/dextran sulphate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.