Patent · US Expired

Budesonide pellets with a controlled released pattern and process for producing the same

US5932249A · kind A · utility

40Cited by

4References

20Claims

0Family size

Assignee

Dr. Falk Pharma Gmbh · DE

Inventors

Peter Gruber · Bottmingen, CH
Hans Joachim Lach · Endingen am Kaiserstuhl, DE
Norbert Otterbeck · Überlingen, DE

Key dates

Filing date	Jul 15, 1996
Grant date	Aug 3, 1999
Priority date	—
Expiry date	Jul 15, 2016

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y304/24
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed are budesonide pellets with a controlled release pattern containing, from the inside to the outside: a) neutral pellets; b) an active principle layer of micronized budesonide and one or more water-soluble auxiliaries; c) a first lacquer coating consisting of 80 to 97% of at least one lacquer insoluble in gastric fluids but soluble in intestinal fluids and 3 to 20% of at least one lacquer insoluble in both gastric and intestinal fluids; and d) a second lacquer coating consisting of at least one lacquer insoluble in gastric and intestinal fluids. The invention also relates to a process for producing budesonide pellets with a controlled release pattern.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.