Melatonin derivative dermocosmetic compositions for whitening/depigmenting the skin
US5932608A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 25, 1997 |
| Grant date | Aug 3, 1999 |
| Priority date | — |
| Expiry date | Jul 25, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/782
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Topically applicable dermocosmetic compositions for whitening/depigmenting human skin, comprise a skin-whitening/depigmenting effective amount of at least one melatonin derivative having the structural formula (I): in which R.sub.1 is a lower alkyl radical, R.sub.2 is a hydrogen atom or a lower alkyl radical, and R.sub.3 is a hydrogen atom or a lower acyl radical, with the proviso that the hydroxyl radical is in the 4-, 6- or 7-position on the indole ring system, or a physiologically acceptable salt, solvate or bioprecursor/prodrug thereof, formulated into a topically applicable, cosmetically/dermatologically acceptable vehicle, carrier or diluent therefor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.