Thioether-containing metal chelating compounds
US5932707A · kind A · utility
5Cited by
3References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 7, 1997 |
| Grant date | Aug 3, 1999 |
| Priority date | — |
| Expiry date | Jul 7, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Ligands for radiopharmaceutical use are capable of chelating radiometal species and of being bound to biological targeting molecules. The ligands have the formula (a) and (b), where A, A'=--SZ or Y, B=O or S, Y=(c), Z=H or a thiol protecting group, m=2 or 3, n=2 or 3, q=0 or 1, R=H or unsubstituted or substituted hydrocarbon and pharmaceutically acceptable salts, provided that at least one CR.sub.2 group represents CO and forms, together with an adjacent N atom; a --CONR-- amide group. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.