Asymmetric synthesis of benzoxazinones
US5932726A · kind A · utility
4Cited by
10References
42Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 11, 1997 |
| Grant date | Aug 3, 1999 |
| Priority date | — |
| Expiry date | Apr 11, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel methods for the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1- benzoxazin-2-one of formula (VI-i) ##STR1## which is useful as a human immunodeficiency virus (HIV) reverse transcriptase inhibitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.