Iridium-catalyzed carbonylation process for the production of a carboxylic acid
US5932764A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 4, 1997 |
| Grant date | Aug 3, 1999 |
| Priority date | — |
| Expiry date | Dec 4, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C51/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the production of a carboxylic acid having n+1 carbon atoms comprises (a) carbonylating with carbon monoxide in a first reaction zone at elevated temperature and pressure an alkyl alcohol having n carbon atoms and/or a reactive derivative thereof to produce a carboxylic acid having n+1 carbon atoms in a liquid reaction composition comprising carboxylic acid product, an iridium catalyst, an alkyl halide co-catalyst, water, an ester of the carboxylic acid product and the alkyl alcohol, and optionally one or more promoters, (b) withdrawing from the first reaction zone at least a portion of the liquid reaction composition together with dissolved and/or entrained carbon monoxide, and passing at least a portion of the withdrawn liquid reaction composition and carbon monoxide to a second reaction zone, ((c)reacting at least 1% of the dissolved and/or entrained carbon monoxide in the withdrawn reaction composition by further carbonylation at elevated temperature and pressure in the second reaction zone to produce further carboxylic acid product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.