Process for preparing dibenzocycloheptene compounds
US5932767A · kind A · utility
1Cited by
4References
2Claims
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Key dates
| Filing date | Dec 22, 1997 |
| Grant date | Aug 3, 1999 |
| Priority date | — |
| Expiry date | Dec 22, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C211/32
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Protriptyline can be prepared from 5-dihydrodibenzocycloheptatriene, by deprotonation, followed by reaction at low temperatures with 1,3-bromochloropropane to give the 5-(chloropropyl)-dibenzocycloheptatriene, which is reacted with methylamine in a displacement reaction to give the protriptyline product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.