Patent · US Expired

Chemo-mechanical expansion delivery system

US5935593A · kind A · utility

43Cited by
24References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 22, 1996
Grant dateAug 10, 1999
Priority date
Expiry dateOct 22, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2533/78
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

System for delivery of a biologically active substance into an environment. First and second chambers are separated by a moveable partition. The first chamber includes a polymer gel network which undergoes a volume change in response to an environmental condition such as pH. The first compartment includes a screen or membrane for confining the polymer gel network while allowing communication with fluid in an environment. The second compartment contains a biologically active compound or drug which is delivered to the environment through an orifice in the second compartment. Upon the occurrence of the triggering environmental condition, the polymer gel network undergoes a volume change which moves the moveable partition expelling the drug through the orifice. Drug delivery is initiated and continues only when the appropriate environmental condition or trigger is met.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.