Acid-labile subunit (ALS) of insulin-like growth factor binding protein complex
US5936064A · kind A · utility
2Cited by
3References
1Claims
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Key dates
| Filing date | Jun 2, 1995 |
| Grant date | Aug 10, 1999 |
| Priority date | — |
| Expiry date | Jun 2, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An acid-labile protein is described that, when incubated with the 53-Kd acid-stable protein occupied by IGF, converts it to a high molecular weight complex, corresponding to the in vivo form of IGF. This protein is called the acid-labile subunit (ALS) of IGF binding protein complex and is provided in biologically pure form. ALS is useful in treating wounds and promoting cellular growth. The nucleic acid encoding ALS, antibodies binding thereto, and fragments thereof are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.