Metallocorrinoids as biologically compatible carriers of pharmacological agents
US5936082A · kind A · utility
12Cited by
0References
17Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 30, 1997 |
| Grant date | Aug 10, 1999 |
| Priority date | — |
| Expiry date | Dec 30, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A purified complex of a metallocorrinoid, such as a vitamin B.sub.12 compound, and a pharmacological agent, such as nitric oxide, that is capable of site-specific delivery of the pharmacological agent in vivo. The pharmacological agent is bound to the metallocorrinoid in a non-donating solvent. The complex is then resuspended in a biocompatible medium and inserted into the recipient. The pharmacological agent then releases in vivo, especially under acidic conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.