Gel formulations for topical drug delivery
US5939090A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 3, 1996 |
| Grant date | Aug 17, 1999 |
| Priority date | — |
| Expiry date | Dec 3, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pharmaceutical gel formulations for topical drug delivery include drug, colloidal silicon dioxide, triacetin and, preferably, propylene glycol. The gel formulations are well suited for topical delivery of the drug 4-amino-2-ethoxymethyl-.alpha.,.alpha.-dimethyl-1H-imidazo4,5-c!quinoline -1-ethanol, which when applied topically induces cytokines, such as interferon and tumor necrosis factor, locally in the skin or mucous membranes of a mammal. The gel formulations are also well-suited for topical delivery of drugs for treatment of diseases involving skin and/or mucosal lesions because the gel formulations do not need to include irritating components.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.