Method for creation of biomimetic surfaces
US5939208A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Nov 7, 1997 |
| Grant date | Aug 17, 1999 |
| Priority date | — |
| Expiry date | Nov 7, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/31855
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
In the present invention method, the surface of articles made of acrylic polymers and methacrylic polymers are converted into thin biomimetic layers by using the process involving at least the following two steps: PA1 (a) The polymer surface is contacted, in the presence of water and for a predetermined reaction time necessary to form a continuous surface layer thinner than about 500 microns, with a solution containing one or more tetraalkylammonium hydroxides of the general formula: EQU R.sub.1 R.sub.2 R.sub.3 R.sub.4 N.sup.+ OH.sup.- where R.sub.1, R.sub.2, R.sub.3, R.sub.4 are the alkyl substituents, in which the sum of the number of carbon atoms is equal to or larger than 8 but smaller than 45; and, PA1 (b) The article is removed from the aqueous reaction solution and excess of tetraalkylammonium hydroxide is removed from the polymer surface by washing the polymer with a liquid miscible with the tetraalkylammonium hydroxide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.