Acetaldehyde and malondialdehyde protein adducts
US5939535A · kind A · utility
2Cited by
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4Claims
0Family size
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Key dates
| Filing date | Apr 8, 1997 |
| Grant date | Aug 17, 1999 |
| Priority date | — |
| Expiry date | Apr 8, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/18
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A novel protein adduct is disclosed which is associated with the presence of alcohol liver disease. The adduct is a hybrid product of malondialdehyde and acetaldehyde which act synergistically to bind hepatic proteins. The adduct is highly immunogenic and fluorescent. Methods of detection are also disclosed including monoclonal and polyclonal antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.