Platelet secretory transport protein
US5939540A · kind A · utility
6Cited by
0References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 7, 1997 |
| Grant date | Aug 17, 1999 |
| Priority date | — |
| Expiry date | Oct 7, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/28
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed is a novel protein designated platelet secretory transport protein (PSTP). PSTP occurs in platelets and binds to syntaxin. An isolated DNA encoding PSTP, vectors and cells containing the DNA, and PSTP specific antibodies are also disclosed. A PSTP antibody can be used to target a compound to an activated platelet in a mammal for diagnostic or therapeutic purposes. Also disclosed is an in vitro screening method for identifying a compound that inhibits PSTP-syntaxin binding, and an in vitro method for identifying a compound that inhibits PSTP gene expression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.