Retention time-locked spectral database for target analyte analysis
US5939612A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 28, 1998 |
| Grant date | Aug 17, 1999 |
| Priority date | — |
| Expiry date | Apr 28, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/8804
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Screening an unknown sample for a plurality of known or "target" analytes may be accomplished by creating and searching a retention time-locked spectral database for the entire chromatographic output of a locked GC system locked to such spectral database. Identification of target analytes having for example, known significant mass spectral ions and mass ion ratios corresponding to known analytes of interest believed to be found within a pre-defined retention time window is improved by direct comparison of significant mass spectral ions and the mass ion ratios within a specified retention time window.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.