Osp A proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines

US5942236A · kind A · utility

Assignees

• SmithKline Beecham Biologicals S.A. · BE
• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US
• Duetsches Krebsforschungszentrum Stiftung des offentlichen Rechts · DE

Inventors

• Yves Lobet · Rixensart, BE
• Markus Simon · Buckenhof, DE
• Ulrich E. Schaible · Freiberg, DE
• Reinhard Wallich · Heidelberg, DE
• Michael Kramer · Freiberg, DE

Key dates

• Filing date: May 16, 1995
• Grant date: Aug 24, 1999
• Expiry date: May 16, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/825
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to novet Borrelia, and OspA antigens derived therefrom. These antigens show little homology with known OspA's and are therefore useful as vaccine and diagnostic reagents. Multicomponent vaccines based on OspA's from different Borrelia groups are also disclosed.