Conversion of compactin to pravastatin by actinomadura
US5942423A · kind A · utility
16Cited by
5References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Aug 24, 1999 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/03
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for converting compactin to pravastatin is described. Compactin is provided and contacted with an agent derived from Actinomadura under conditions in which the agent converts compactin to pravastatin. Also described are an Actinomadura strain, an Actinomadura cell free extract, an Actinomadura hydroxylase, and a method for lowering cholesterol levels in mammals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.