Haemoglobin
US5942488A · kind A · utility
2Cited by
0References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 17, 1996 |
| Grant date | Aug 24, 1999 |
| Priority date | — |
| Expiry date | Jun 17, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a mutant human .beta. globin modified so as to exhibit, when present as part of a hemoglobin molecule, an altered bicarbonate effect compared to the unmodified .beta. globin. The .beta. globin is modified to contain at positions 29-41 at least two non-wild type amino acid residues selected from the group consisting of amino acid residues 29-41 of crocodile .beta.-globin SEQ ID NO:2 to produce an enhanced bicarbonate effect.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.