Method of promoting bone growth with hyaluronic acid and growth factors
US5942499A · kind A · utility
33Cited by
38References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 5, 1997 |
| Grant date | Aug 24, 1999 |
| Priority date | — |
| Expiry date | Mar 5, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A bone growth-promoting composition is provided comprising hyaluronic acid and a growth factor. The composition has a viscosity and biodegradability sufficient to persist at the site of desired bone growth for a period of time sufficient to promote the bone growth. Preferably hyaluronic acid is used in a composition range of 0.1-4% by weight and preferred growth factor is bFGF, present in a concentration range of about 10.sup.-6 to 100 mg/ml.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.