Photo-stable cosmetic and pharmaceutical formulations containing UV-filters

US5945091A · kind A · utility

Assignee

• BASF SE

Inventors

• Thorsten Habeck · Meckenheim, DE
• Alexander Aumuller · Neustadt, DE
• Volker Schehlmann · Schifferstadt, DE
• Horst Westenfelder · Neustadt, DE
• Thomas Wunsch · Speyer, DE

Key dates

• Filing date: Nov 18, 1997
• Grant date: Aug 31, 1999
• Expiry date: Nov 18, 2017

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2800/52
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of using compounds of formula I ##STR1## in which the C.dbd.C double bond is present in E and/or Z configuration and the variables have the following meanings: PA1 R.sup.1 denotes COOR.sup.5, COR.sup.5, CONR.sup.5 R.sup.6, CN, O.dbd.S(--R.sup.5).dbd.O, O.dbd.S(--OR.sup.5).dbd.O, R.sup.7 O--P(--OR.sup.8).dbd.O; PA1 R.sup.2 denotes COOR.sup.6, COR.sup.6, CONR.sup.5 R.sup.6, CN, O.dbd.S(--R.sup.6).dbd.O, O.dbd.S(--OR.sup.6).dbd.O, R.sup.7 O--P(--OR.sup.8).dbd.O; PA1 R.sup.3 denotes hydrogen, an optionally substituted aliphatic, cycloaliphatic, araliphatic or aromatic radical having in each case up to 18 carbon atoms; PA1 R.sup.4 denotes an optionally substituted aromatic or heteroaromatic radical containing from 5 to 12 ring atoms; PA1 R.sup.5 to PA1 R.sup.8 independently denote hydrogen, an open-chain or branched-chain aliphatic, araliphatic, cycloaliphatic or optionally substituted aromatic radical containing in each case up to 18 carbon atoms, where the variables R.sup.3 to R.sup.8 may also form, together with the carbon atoms to which they are attached, a 5-membered or 6-membered ring, which may be anellated if desired, as UV filters, particularly UV-A filters, in cosmeti…