Method for assaying bilirubin .delta. fractions
US5945298A · kind A · utility
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6References
5Claims
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Key dates
| Filing date | Feb 26, 1998 |
| Grant date | Aug 31, 1999 |
| Priority date | — |
| Expiry date | Feb 26, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/90206
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
By making a bilirubin oxidase derived from the genus Pleurotus to act on a living body fluid sample in the presence of at least one of a cationic surfactant such as alkyltrimethylammonium salt, etc. and a nonionic surfactant such as polyoxyethylenealkyl ether, etc., only bilirubin non-.delta. fractions of the living body fluid sample can be oxidized, while keeping a bilirubin .delta. fraction remaining as unreacted. Thus, the bilirubin non-.delta. fractions and .delta. fraction of the living body fluid sample can be exactly quantitatively determined by action of the bilirubin oxidase on the sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.