Patent · US Expired

Oligonucleotides and methods for inhibiting cellular proliferation

US5945336A · kind A · utility

1Cited by
6References
44Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 21, 1997
Grant dateAug 31, 1999
Priority date
Expiry dateNov 21, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/315
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to methods of treating disease-associated cellular proliferation using oligonucleotides. In particular, it relates to the use of oligonulceotides which are substantially complementary to interleukin-6 receptor mRNA sequences. In the form of pharmaceutical compositions, these oligonucleotides are suitable for administration to human subjects for the treatment of abnormal cellular proliferation due to such diseases as cancer, autoimmune disorders and viral infection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.