(R)-5-bromo-N-(1-ethyl-4-methylhexahydr o-1H-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridinecarboxamide, process for producing the same and medicinal composition containing the same
US5945415A · kind A · utility
5Cited by
2References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 23, 1998 |
| Grant date | Aug 31, 1999 |
| Priority date | — |
| Expiry date | Jan 23, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D243/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention discloses a compound which is expressed by formula (I) below: ##STR1## or physiologically acceptable acid addition salts thereof. The claimed compound exhibits excellent antiemetic effect based on its potent serotonin S.sub.3 and dopamine D.sub.2 receptor antagonistic activities, and is useful for treatment or prophylaxis of various gastrointestinal symptoms which are associated with various diseases and drug administration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.