Influenza vaccine
US5948410A · kind A · utility
63Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 6, 1998 |
| Grant date | Sep 7, 1999 |
| Priority date | — |
| Expiry date | Apr 6, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16234
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is concerned with an Influenza surface antigen vaccine obtainable by production from Influenza Viruses propagated on animal cell culture and having a host cell DNA content equal to or less than 25 pg per dose. The present invention is also concerned with a method for the preparation of surface antigen proteins from Influenza Viruses propagated on an animal cell culture comprising the subsequent steps of: PA1 a. treatment of the whole virus containing fluid obtained from the cell culture with a DNA digesting enzyme, and PA1 b. adding a cationic detergent, followed by isolation of the surface antigen proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.