Patent · US Expired

Modulators of BRCA1 activity

US5948643A · kind A · utility

8Cited by
0References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 13, 1997
Grant dateSep 7, 1999
Priority date
Expiry dateAug 13, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K14/4702
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Compositions of matter consisting of a family of related nucleotide sequences that encode proteins, termed BRCA1 Modulator Proteins, that bind to the tumor suppressor gene product BRCA1, and methods of using the nucleotide sequences and the proteins encoded thereby, to diagnose and/or treat disease where the BRCA1 Modulator Proteins have an apparent molecular weight of 45-97 kdaltons and are characterized by having at least one leucine zipper domain, and optionally a zinc finger domain.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.