Patent · US Expired

Use of R-(+)-.alpha.-lipoic acid, R-(-)-dihydrolipoic acid and metabolites in the form of the free acid or as salts or esters or amides for the preparation of drugs for the treatment of diabetes mellitus as well as of its sequelae

US5948810A · kind A · utility

8Cited by

1References

1Claims

0Family size

Assignee

Asta Medica Aktiengesellschaft · DE

Inventors

Klaus Wessel · Frankfurt, DE
Harald Borbe · Mainz, DE
Heinz Ulrich · Niedernberg, DE
Helmut Hettche · Dietzenbach, DE
Hans Bisswanger · Bodelshausen, DE
Lester Packer · Berkeley, US
Amira Klip · Toronto, CA

Key dates

Filing date	Jun 19, 1997
Grant date	Sep 7, 1999
Priority date	—
Expiry date	Jun 19, 2017

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P3/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to the use of R-(+)-.alpha.-lipoic acid, R-(-)-dihydrolipoic acid or their metabolites, salts, esters and amides for the synthesis of drugs for the treatment of diabetes mellitus of types I and II, compensated and decompensated insulin resistance and sequelae or late complications of diabetes mellitus, such as cataracts, polyneuropathy, nephropathy, as well as sequelae or late complications of insulin resistance.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.