Patent · US Expired

Photo-activatable biotin derivatives and their use to reduce interference in immunoassays

US5952185A · kind A · utility

6Cited by

1References

17Claims

0Family size

Assignee

Boehringer Mannheim GmbH · DE

Inventors

Erasmus Huber · Garching bei München, DE
Michael Wiedmann · Penzberg, DE
Frederic Donie · Penzberg, DE

Key dates

Filing date	Oct 27, 1997
Grant date	Sep 14, 1999
Priority date	—
Expiry date	Oct 27, 2017

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S530/807
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention addresses new photo-activatable biotin derivatives having the formula I ##STR1## wherein R=(CH.sub.2).sub.n --O.sub.m !.sub.q --(CH.sub.2).sub.r --O.sub.s !.sub.t --(CH.sub.2).sub.p PA1 with n,r=2,3; m,s=0,1; q+t=1-4; p=1-4, PA1 wherein the sum of all CH.sub.2 groups does not exceed 10 PA1 and wherein R1 as a single or multiple substituent is hydrogen, C.sub.1 -C.sub.5 alkyl, NH.sub.2, COOH, F, Cl, or Br. and their preparation, their use to inactivate streptavidin, the use of the inactivated streptavidin to reduce interference in immunoassays.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.