Retroviral vectors produced by producer cell lines resistant to lysis by human serum
US5952225A · kind A · utility
13Cited by
3References
21Claims
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Key dates
| Filing date | Aug 17, 1995 |
| Grant date | Sep 14, 1999 |
| Priority date | — |
| Expiry date | Aug 17, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/13043
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Retroviral which are resistant to inactivation by human serum. The retroviral vectors are produced in a cell line which is resistant to lysis by human serum, such cell lines including the HOS, Mv-1-Lu, HT1080, TE671, and human 293 cell lines, as well as cell lines derived therefrom. Such retroviral vectors are especially useful as in vivo gene delivery vehicles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.