Pyrrolidine compounds useful in the treatment of diabetes
US5952363A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 5, 1998 |
| Grant date | Sep 14, 1999 |
| Priority date | — |
| Expiry date | Mar 5, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D207/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel pyrrolidine compounds having the general formula I ##STR1## and pharmaceutically acceptable acid addition salts or hydrates or prodrugs thereof, wherein R.sup.1 is straight or branched C.sub.1-14 -alkyl optionally substituted with C.sub.3-7 -cycloalkyl, C.sub.1-6 -alkoxy, phenoxy, perhalomethyl, halogen, optionally substituted phenyl; PA1 CR.sup.2 is optionally C.dbd.R.sup.2 or C--R.sup.2 PA1 R.sup.2 is oxygen, hydroxy, halogen, amino or mercapto, PA1 R.sup.3 and R.sup.4 independently are hydroxy, halogen, amino or mercapto, the use of these compounds as medicament, the use of these medicaments in the treatment of diabetes, pharmaceutical compositions containing these compounds and methods of preparing the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.