Method for producing optically-active 2-piperazinecarboxylic acid derivatives
US5952503A · kind A · utility
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Key dates
| Filing date | Aug 26, 1998 |
| Grant date | Sep 14, 1999 |
| Priority date | — |
| Expiry date | Aug 26, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D241/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Optically-active 2-piperazinecarboxylic acid derivatives are produced through diastereomer salt resolution using optically-active acidic amino acid derivative as the resolving reagent. In this method, the recovery of the resolving reagent used is high, and the production efficiency to produce the optically-active products is high. As the optically-active acidic amino acid derivatives, usable are optically-active, N-acylated acidic amino acid derivatives and optically-active, N-sulfonylated acidic amino acid derivatives.
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