Patent · US Expired

Cross-linked microparticles and their use as therapeutic vehicles

US5955108A · kind A · utility

32Cited by
4References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 16, 1997
Grant dateSep 21, 1999
Priority date
Expiry dateJun 16, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K47/643
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A sterile powder comprising microparticles, 0.1 to 50 .mu.m in diameter, obtainable by spray-drying and cross-linking a water-soluble material having free functional groups, is characterized in that the microparticles are hydrophilic, can be reconstituted in water to give a monodisperse suspension, and have retained said groups available for derivatization. The particles are linked to drugs or other functional molecules, and used as vehicles in therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.