Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5955294A · kind A · utility
3Cited by
31References
3Claims
0Family size
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Key dates
| Filing date | Apr 19, 1996 |
| Grant date | Sep 21, 1999 |
| Priority date | — |
| Expiry date | Apr 19, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4354
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Proteins which have activity as anticoagulants and/or serine protease inhibitors and have at least one NAP domain and are described. Certain of these proteins have factor Xa inhibitory activity and others have activity as inhibitors of factor VIIa/TF. These proteins can be isolated from natural sources as nematodes, chemically synthesized or made by recombinant methods using various DNA expression systems.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.