Patent · US Expired

Self-assembling polynucleotide delivery system

US5955365A · kind A · utility

21Cited by
2References
33Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 7, 1995
Grant dateSep 21, 1999
Priority date
Expiry dateJun 7, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08G2261/312
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention provides a self-assembling polynucleotide delivery system comprising components aiding in the delivery of the polynucleotide to the desired address which are associated via noncovalent interactions with the polynucleotide. The components of this system include DNA-masking components, cell recognition components, charge-neutralization and membrane-permeabilization components, and subcellular localization components. Specific compounds useful in this system are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.