Oxazolidinone antibacterial agent with tricyclic substituents
US5955460A · kind A · utility
3Cited by
0References
8Claims
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Assignee
Inventor
Key dates
| Filing date | Feb 15, 1999 |
| Grant date | Sep 21, 1999 |
| Priority date | — |
| Expiry date | Feb 15, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides novel oxazolidinone derivatives represented by chemical Formula (I), or pharmaceutically acceptable salts thereof: ##STR1## wherein X is NR.sub.1, CR.sub.2 R.sub.3, O, S, SO, or SO.sub.2 ; and Z is NR.sub.4, S, SO, SO.sub.2 or O. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci and streptococci, as well as anaerobic organisms such as bacteroides and clostridia species, and acid-fast organisms such as Mycobacterium tuberculosis and Mycobacterium avium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.