Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
US5955490A · kind A · utility
83Cited by
16References
12Claims
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Key dates
| Filing date | Jun 5, 1995 |
| Grant date | Sep 21, 1999 |
| Priority date | — |
| Expiry date | Jun 5, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of detecting and treating rapidly growing exogenous cells, such as Protista, or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5-aminolevulinic acid or precursor thereof is administered to the patient, or contacted to the exogenous cells, in an amount sufficient to induce synthesis fluorescence and/or photosensitizing concentrations of a protoporphyrin IX in the exogenous cells, followed by exposure of the exogenous cells to light of photoactivating wavelengths.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.