pH dependent polymer micelles
US5955509A · kind A · utility
221Cited by
6References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 23, 1997 |
| Grant date | Sep 21, 1999 |
| Priority date | — |
| Expiry date | Apr 23, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1075
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the use of poly(vinyl N-heterocycle)-block-poly(alkylene oxide) copolymers in micelle containing pharmaceutical formulations. The copolymers advantageously respond to pH differences in the environment to which they are exposed forming micelles at higher pH values. The micelles, which comprise a therapeutic compound and a copolymer, deliver drug in a pH dependent manner.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.