Patent · US Expired

Vaccines for nontypable haemophilus influenzae

US5955580A · kind A · utility

34Cited by
7References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 23, 1995
Grant dateSep 21, 1999
Priority date—
Expiry dateMay 23, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/40
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Protein "e" of H. influenzae, a lipoprotein of approximately 28,000 daltons, has been purified and sequenced. Protein "e" and peptides or proteins having a shared epitope, can be used to vaccinate against nontypable (and typable) H. influenzae and to prevent otitis media caused by H. influenzae. For this purpose, protein "e" or derivatives thereof can be produced in native, synthetic or recombinant forms and can be administered alone or in conjunction with other antigens of H. influenzae. Protein "e" can also be used in multivalent vaccines designed for H. influenzae and one or more other infectious organisms.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.