Method for preparing radionuclide-labeled chelating agent-ligand complexes
US5958374A · kind A · utility
20Cited by
6References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 17, 1996 |
| Grant date | Sep 28, 1999 |
| Priority date | — |
| Expiry date | Dec 17, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Radionuclide-labeled chelating agent-ligand complexes that are useful in medical diagnosis or therapy are prepared by reacting a radionuclide, such as .sup.90 Y or .sup.111 In, with a polyfunctional chelating agent to form a radionuclide chelate that is electrically neutral; purifying the chelate by anion exchange chromatography; and reacting the purified chelate with a targeting molecule, such as a monoclonal antibody, to form the complex.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.